Details for Dr. Helen Gallagher BSc, PhD

Position:
Institution:	University College Dublin
Curriculum Vitae:	http://www.ucd.ie/conway/cv_284.html
Email:	helen.gallagher@ucd.ie

Active Research Topics:
	Various Cancer-related Interests
	Signalling Mechanisms regulating neuroplastic events in the central nervous system and their application to rational drug design and target validation
	Cell Cycle related protein regulation and relevance to Alzheimers disease
	development of in vitro screening systems for detection of teratogen and endocrine disrupting activities

General Research Interest(s) :
	Alzheimers Disease
	Androgen Independence
	Angiogenesis
	Animal Models
	Apoptosis
	Apoptosis Inhibitors
	Biomarkers
	Brain
	Cancer Strategies { General }
	Cell Adhesion
	Cell Cycle & Signalling
	Cell Cycle Signalling
	Central Nervous System
	Chemotherapy
	Clinical Studies
	Drug Design & Synthesis
	Drug Therapy
	Enabling Technologies { Other }
	Metabolism
	Nerves, Nodes & Synapses
	Neurological Diseases & Complications
	Regulation Mechanisms
	Teratogen
	Teratogens { Effect of }
	Various hormones

Key publications for Dr. Helen Gallagher BSc, PhD:
	Pentyl-4-yn-valproic acid reverses age-associated memory impairment in the Wistar rat A. G. Foley, H. C. Gallagher, K. J. Murphy and C. M. Regan Neurobiol Aging  Vol:25  Issue:4  Pages:539-46  2004  Apr  Accession No. 15013575
	Valproate activates phosphodiesterase-mediated cAMP degradation: relevance to C6 glioma G1 phase progression H. C. Gallagher, C. L. Bacon, O. A. Odumeru, K. F. Gallagher, T. Fitzpatrick and C. M. Regan Neurotoxicol Teratol  Vol:26  Issue:1  Pages:73-81  2004  Jan  Accession No. 15001216
	Differential enantioselective effects of pentyl-4-yn-valproate on spatial learning in the rat, and neurite outgrowth and cyclin D3 expression in vitro E. D. O'Loinsigh, L. M. Gherardini, H. C. Gallagher, A. G. Foley, K. J. Murphy and C. M. Regan J Neurochem  Vol:88  Issue:2  Pages:370-9  2004  Jan  Accession No. 14690525
	The 5-HT(6) receptor antagonist SB-271046 reverses scopolamine-disrupted consolidation of a passive avoidance task and ameliorates spatial task deficits in aged rats A. G. Foley, K. J. Murphy, W. D. Hirst, H. C. Gallagher, J. J. Hagan, N. Upton, F. S. Walsh and C. M. Regan Neuropsychopharmacology  Vol:29  Issue:1  Pages:93-100  2004  Jan  Accession No. 14571256
	Antiproliferative action of valproate is associated with aberrant expression and nuclear translocation of cyclin D3 during the C6 glioma G1 phase C. L. Bacon, H. C. Gallagher, J. C. Haughey and C. M. Regan J Neurochem  Vol:83  Issue:1  Pages:12-Sep  2002  Oct  Accession No. 12358724
	Automated in vitro screening of teratogens P. S. Walmod, A. Berezin, H. C. Gallagher, U. Gravemann, E. A. Lepekhin, V. Belman, C. L. Bacon, H. Nau, C. M. Regan, V. Berezin and E. Bock Toxicol Appl Pharmacol  Vol:181  Issue:1  Pages:Jan-15  2002  May  Accession No. 12030837
	Pentyl-4-yn-valproic acid enhances both spatial and avoidance learning, and attenuates age-related NCAM-mediated neuroplastic decline within the rat medial temporal lobe K. J. Murphy, G. B. Fox, A. G. Foley, H. C. Gallagher, A. O'Connell, A. M. Griffin, H. Nau and C. M. Regan J Neurochem  Vol:78  Issue:4  Pages:704-14  2001  Aug  Accession No. 11520891
	CREB phosphorylation coincides with transient synapse formation in the rat hippocampal dentate gyrus following avoidance learning C. O'Connell, H. C. Gallagher, A. O'Malley, M. Bourke and C. M. Regan Neural Plast  Vol:7  Issue:4  Pages:279-89  2000  Jan  Accession No. 11486487
	Anti-ischemic and cognition-enhancing properties of NNC-711, a gamma-aminobutyric acid reuptake inhibitor A. W. O'Connell, G. B. Fox, C. Kjoller, H. C. Gallagher, K. J. Murphy, J. Kelly and C. M. Regan Eur J Pharmacol  Vol:424  Issue:1  Pages:37-44  2001  Jul  Accession No. 11470258
	Protein kinase C delta regulates neural cell adhesion molecule polysialylation state in the rat brain H. C. Gallagher, K. J. Murphy, A. G. Foley and C. M. Regan J Neurochem  Vol:77  Issue:2  Pages:425-34  2001  Apr  Accession No. 11299305
	Consolidation of passive avoidance learning is associated with transient increases of polysialylated neurons in layer II of the rat medial temporal cortex G. B. Fox, G. Fichera, T. Barry, A. W. O'Connell, H. C. Gallagher, K. J. Murphy and C. M. Regan J Neurobiol  Vol:45  Issue:3  Pages:135-41  2000  Nov  Accession No. 11074459
	Regulation of neural cell adhesion molecule polysialylation state by cell-cell contact and protein kinase C delta H. C. Gallagher, O. A. Odumeru and C. M. Regan J Neurosci Res  Vol:61  Issue:6  Pages:636-45  2000  Sep  Accession No. 10972960
	A synthetic peptide ligand of neural cell adhesion molecule (NCAM) IgI domain prevents NCAM internalization and disrupts passive avoidance learning A. G. Foley, B. P. Hartz, H. C. Gallagher, L. C. Ronn, V. Berezin, E. Bock and C. M. Regan J Neurochem  Vol:74  Issue:6  Pages:2607-13  2000  Jun  Accession No. 10820224
	Antiproliferative actions of inhalational anesthetics: comparisons to the valproate teratogen G. O'Leary, C. L. Bacon, O. Odumeru, C. Fagan, T. Fitzpatrick, H. C. Gallagher, D. C. Moriarty and C. M. Regan Int J Dev Neurosci  Vol:18  Issue:1  Pages:39-45  2000  Feb  Accession No. 10708904