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DMMC COURSES & WORKSHOPS

MICROARRAY EXPERIMENTAL DESIGN
17 April 2007; 0930-1300
Venues: Montgomery Lecture Theatre, Trinity Centre for Health Sciences, St James's Hospital, Dublin 8 (location)

Applications are closed
This course was oversubscribed. If you are interested in a future running of this course, please send an email to education@dmmc.ie

Expression microarrays produce large amounts of data and are relatively expensive. Therefore, it is essential that projects involving microarrays are carefully considered from the outset. What biological question(s) are you asking? What are the array types available and how do they differ? How many arrays will you need? What quantity and quality of RNA sample is required? How many replicates? Should you pool samples? What are the sources of variation? How can you minimise and control for non-informative experimental variation? What are the statistical issues that you need to be aware of at the experimental design stage? Time spent in designing a good microarray experiment will help to minimise difficulties in data analysis and reduce costly repeats. This half-day DMMC Course comprises lectures covering the basics of designing a microarray project. The morning concludes with a breakout session to discuss participants experimental design issues. Please note, a separate DMMC Microarray Data Analysis course runs in May 2007.

This course can accommodate a maximum of 45 attendees.

Tue 17 Apr; 0930-1300
0930 Introduction - why run a microarray experiment?
Prof John O'Leary, TCD
1000 Array types and RNA Preps
Prof William Gallagher, UCD
1045 Coffee/Tea
1100 Project design Dr Orla Sheils, TCD
1145 Statistical elements of project design
Dr Patrick Dicker, RCSI
1215 Breakout session

Course Instructors
Dr Patrick Dicker
(Royal College of Surgeons in Ireland)
Prof William Gallagher (UCD Conway Institute of Biomolecular & Biomedical Science)

Prof John O'Leary (Institute of Molecular Medicine and Coombe Women's Hospital, TCD)
Dr Orla Sheils (Institute of Molecular Medicine, TCD)