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DMMC COURSES & WORKSHOPS
IMMUNOBIOLOGY
10 Jan - 7 Mar 2007; 1015-1245 weekly
(Wed)
Venue: Education & Research Centre, St Vincent's University
Hospital, Dublin 4 (location)
Applications
are now closed
Online application period was:
27 Nov - 22 Dec 2006
The
aim of this course is to introduce students to the basic concepts
and terminology required to understand immunology. At the end of
the course, participants should be familiar with the terms and models
of innate and adaptive immunity and be conversant with the names
and functions of the organs, cells, molecules and genes involved
in initiating and mediating immune responses. Participants should
be able to explain fundamental immunological concepts and discuss
the roles of key components of the immune system including acute
phase proteins, complement, haematopoietic cells, immunoglobulins
and cytokines in protecting against disease. The course will also
provide an understanding of some basic concepts of immunological
dysregulation seen in inflammatory and autoimmune diseases, allergy,
malignancy and immunopathogenesis and appreciate genomic influences
on these processes.
| Wed
10 Jan; 1015-1245 |
| Introductory
overview
Prof Cliona O'Farrelly, UCD |
| Organs,
cells, molecules and genes of the immune system; introduction
to innate immunity |
| |
|
| Wed
17 Jan; 1015-1245 |
| Innate immunity I
Dr John Baugh, UCD |
| Toll like receptors;
anti-microbial peptides; complement |
| |
|
| Wed
24 Jan; 1015-1245 |
| Innate immunity
II Dr John Baugh, UCD |
| Inflammation; cytokines;
anti-inflammatory mechanisms |
| |
|
| Wed
31 Jan; 1015-1245 |
Linking innate
and adaptive immunity
Prof
Cliona O'Farrelly, UCD
|
| Cytokines; chemokines;
Dendritic cells (DCs); Natural Killer cells (NK); introduction
to adaptive immunity |
| |
|
| Wed
7 Feb; 1015-1245 |
Antigen
processing and presentation
Dr Elizabeth Ryan, St. Vincent's University
Hospital |
| Major
Histocompatability Complex (MHC); class I; class II |
| |
|
| Wed
14 Feb; 1015-1245 |
| Cellular
and molecular components of adaptive immunity I
Prof Cliona O'Farrelly, UCD |
| T
cells; CD3; CD4; CD8; TCR; T cell activation; T cell development |
| |
|
| Wed
21 Feb; 1015-1245 |
Cellular
and molecular components of adaptive immunity II
Prof Cliona O'Farrelly, UCD |
| B
cells; antibodies IgM; IgD; IgG; IgA; Ige; allergy
|
| |
|
| Wed
28 Feb; 1015-1245 |
Effector
mechanisms in immunology
Dr Elizabeth Ryan, St. Vincent's
University Hospital |
| How
the immune system protects against infection (phagocytosis;
opsonisation; cytotoxicity; apoptosis; NK cell activity; cell
killing; C' activation); vaccination |
| |
|
| Wed
7 Mar; 1015-1245 |
Immunological
dysregulation and intervention
Prof Cliona O'Farrelly, UCD
Dr Jean Fletcher, TCD
Dr Doug Veale, St. Vincent's University Hospital |
| Autoimmunity
- Rheumatoid Arthritis and Multiple Sclerosis; mechanisms of
disease; immunogenomics; immunotherapy |
Recommended Text
Immunobiology (6th Ed). C.A. Janeway, P. Travers, M. Walport,
M. Shlomchik (Garland / Churchill Livingstone).
The previous edition is accessible in the Bookshelf
section of the NCBI website
Course Leader
Prof
Cliona O'Farrelly
Education & Research Centre,
St. Vincent's University Hospital
Email: cliona.ofarrelly@ucd.ie
Contributors
Dr
Elizabeth Ryan (St. Vincent's University Hospital)
Dr
John Baugh (UCD Conway Institute of Biomolecular & Biomedical
Science)
Dr Jean Fletcher (School of Biochemistry & Immunology, TCD)
Dr
Doug Veale (St. Vincent's University Hospital)
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