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DMMC COURSES & WORKSHOPS

EPIGENETICS: FROM MECHANISMS TO MEDICINES
A DMMC International Workshop

Mon 25 - Tue 26 June 2007
(Welcome Reception on Sun 24 June)
Venue:
O’Reilly Hall, University College Dublin (location)

 Quicklink to items on this page:
?a href="#Epigenetics_2007_PROGRAMME">PROGRAMME        FACULTY        ?a href="#Epigenetics_2007_SPONSORS">SPONSORS

This Workshop has External Continuing Medical Education (CME) Credits from the Royal College of Physicians of Ireland (8 Credits for Day 1 and 9 Credits for Day 2) and External Continuing Professional Development (CPD) Credits from the Royal College of Physicians, London (12 Credits).

Application for this Workshop is open to Ireland-based and International Scientists & Clinicians.
Registration rates: €150 for students, €250 for others.
Registration has closed.

View the Workshop Report (544KB PDF)

 Download Supporting Material :

?font size="2">Workshop Poster (1.16MB PDF)

?em>Workshop Programme to Print (301KB PDF)

?font size="2">Guidelines for Poster Abstract Submission (62KB PDF)

?em>Workshop Educational Objectives (127KB PDF)

?em>Accommodation Guide (69KB PDF)

?em>'Things to do in Dublin' guide (476KB PDF)

The Epigenetics: From Mechanisms To Medicines workshop, open to an Ireland-based and international audience, concentrates on the latest developments worldwide in:

  • study of epigenetic mechanisms;
  • techniques and technologies used;
  • application of knowledge of epigenetic mechanisms in the clinic.
In line with the DMMC Education & Training remit to provide the knowledge tools for translational medicine, this workshop is designed to encapsulate current basic and clinical research and provide a glimpse of future potential for an audience of bioscientists and physicians with an interest in epigenetics.

Using the excellent conference facilities of the O’Reilly Hall on the University College Dublin campus, the Epigenetics: From Mechanisms To Medicines workshop brings together internationally renowned speakers, technology developers, and participants based worldwide to interact in the lecture hall, in techniques sessions, in poster sessions, and during informal gatherings. Outside of the intensive two-day workshop schedule, participants may wish to sample the historical sights and cosmopolitan atmosphere of Dublin or venture further afield around Ireland.

WELCOME (Sunday 24 June)
1700 Early Registration
1800-2000 Wine Reception with Music

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DAY 1: EPI-MECHANISMS (Monday 25 June)
0800 Registration & Light Breakfast
0825 Opening of Workshop
Dr Mark Watson (DMMC)
0830 Welcome & Overview of Day 1
Dr Amanda McCann (University College Dublin) & Dr Steven Gray (Trinity College Dublin)
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Session 1: CHROMATIN ?/font>Chair: Dr Steven Gray
0840 Mechanisms and Functions of Epigenetic Reprogramming in Mammalian Development Prof Wolf Reik (The Babraham Institute, Cambridge, UK) abstract
0930 Epigenetic Aspects of Centromere Inheritance and Function?strong>?/strong>
Prof Kevin Sullivan (National University of Ireland, Galway) abstract
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1020 Coffee/Tea + Poster Viewing + Meet Our Sponsors
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Session 2: RNA AS A REGULATOR
                 Chair: Dr Amanda McCann
1050 miRNAs & Cancer Prof Orla Sheils (Trinity College Dublin) abstract
1140 Maternally expressed microRNAs as trans-regulator at the callipyge locus?
Dr Carole Charlier (University of Liège, Belgium) abstract
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1230 Poster Talk 1
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Session 3: HISTONE MODIFICATIONS
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Chair: Prof Wolf Reik
1240 The Histone Code
Prof Bryan Turner (University of Birmingham, UK) abstract
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1330 Lunch + Poster Viewing + Meet Our Sponsors
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1430 Chemical Biology Studies of Chromatin-Modifying Enzymes
Prof Stuart L. Schreiber (Broad Institute of Harvard and MIT, USA) abstract
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1520 Poster Talk 2
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1530 TECHNIQUES WORKSHOP 1
Discovery of DNA Hypermethylation Using a DHPLC Screening Strategy
Dr Antoinette Perry (Trinity College Dublin) abstract
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1610 Coffee/Tea + Poster Viewing + Meet Our Sponsors
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1640 Poster Talk 3
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1650 TECHNIQUES WORKSHOP 2
A Novel Method for Analysis of 5-Methylcytosine in DNA by Capillary Electrophoresis Mobility Shift
Dr Mark Lynch (Application Specialist, Applied Biosystems) abstract
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1730-1830 DAY 1 KEYNOTE LECTURE
      ?(Sponsored by AIB)
?/font> Male-Line Transgenerational Responses -
A New Aspect of Human Inheritance?
Prof Marcus Pembrey (UCL Institute of Child Health, UK) abstract
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1900 Workshop Buffet Dinner with Jazz Band

DAY 2: EPI-THERAPEUTICS (Tuesday 26 June)
0730 Light Breakfast
0800 Overview of Day 2
Dr Amanda McCann (University College Dublin) & Dr Steven Gray (Trinity College Dublin)
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Session 4: INTRODUCTION TO EPIGENETIC DRUGS ?/font>Chair: Dr Kay Nolan
0810 An Introduction to DNA Methyltransferase Inhibitors
Dr Helen Gallagher (University College Dublin) abstract
0840 Histone Deacetylase Inhibitors
Dr Steven Gray (Trinity College Dublin) abstract
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Session 5: STEM CELLS  Chair: Prof Peter Jones
0910 The epigenetic landscape of stem cells
Dr Kay Nolan (University College Dublin) abstract
0940 Stem cell chromatin patterns - a blueprint for DNA hypermethlation?
Dr Joyce Ellen Ohm (Johns Hopkins University, USA) abstract
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1030 Coffee/Tea + Poster Viewing + Meet Our Sponsors
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1100 Poster Talk 4
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Session 6: ENVIRONMENT INTERACTIONS
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Chair: Prof Bryan Turner
1110 Epigenetic Transgenerational Actions of Endocrine Disruptors on Reproduction, Disease and Evolution
Prof Michael Skinner (Washington State University, USA) abstract
1200 Endocrine Active Compounds and the Fetal Epigenome
Dr Dana Dolinoy (Duke University Medical Center, USA) abstract
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1250 Lunch + Poster Viewing + Meet Our Sponsors
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1350 Poster Talk 5
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Session 7: EPIGENETICS & DISEASE
                 Chair: Dr Joyce Ellen Ohm
1400 Imprinting and ART (Assisted Reproductive Technology)
Prof Eamonn Maher (University of Birmingham, UK) abstract
1450

DNA Methylation and Haematological Malignancies
Prof Allen Yang (USC / Norris Comprehensive Cancer Center, USA) abstract

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1540 Coffee/Tea + Poster Viewing + Meet Our Sponsors
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1610 Therapeutic Potential of Targeting the Epigenome in Neurodegenerative Conditions
Dr Hoon Ryu (Boston University School of Medicine) abstract
1700 Leaving an Imprint on Cancer
Dr Amanda McCann (University College Dublin) abstract
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1740 Announcement of Poster Competition Winners
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1745 DAY 2 KEYNOTE LECTURE
(Sponsored by the Irish Cancer Society)
?/font> Cancer Epigenomics
Prof Peter Jones (USC / Norris Comprehensive Cancer Center, USA) abstract
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1845 Close of Workshop
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Workshop Organisers
Dr Amanda McCann (UCD Conway Institute of Biomolecular & Biomedical Research)
Dr Steven Gray (Institute of Molecular Medicine, St James’s Hospital & TCD)
Dr Mark Watson (DMMC Education Coordinator)

Workshop Faculty
Dr Carole Charlier (University of Liège, Belgium)
Dr Dana Dolinoy (Duke University Medical Center, USA)
Dr Helen Gallagher (UCD Conway Institute of Biomolecular & Biomedical Research)
Prof Peter Jones (USC / Norris Comprehensive Cancer Center, USA)
Dr Mark Lynch (Applied Biosystems)
Prof Eamonn Maher (University of Birmingham, UK)
Dr Kay Nolan (School of Biological and Environmental Science, UCD)
Dr Joyce Ellen Ohm (Johns Hopkins University, USA)
Prof Marcus Pembrey (UCL Institute of Child Health, UK)
Dr Antoinette Perry (Institute of Molecular Medicine, TCD)
Prof Wolf Reik (The Babraham Institute, Cambridge, UK)
Dr Hoon Ryu (Boston University School of Medicine)
Prof Stuart L. Schreiber (Broad Institute of Harvard and MIT, USA)

Prof Orla Sheils (Trinity College Dublin)

Prof Michael Skinner (Washington State University, USA)
Prof Kevin Sullivan (National University of Ireland, Galway)
Prof Bryan Turner (University of Birmingham, UK)
Prof Allen Yang (USC / Norris Comprehensive Cancer Center, USA)

Workshop Sponsors

Irish Cancer Society

Platinum Sponsor

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Diagenode sa

Gold Sponsor

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Brennan & Company
Silver Sponsor
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Cambridge Bioscience

Silver Sponsor

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Silver Sponsor

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Silver Sponsor

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Silver Sponsor

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NimbleGen Systems Inc

Silver Sponsor

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AIB


CSHL Press
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