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DMMC COURSES & WORKSHOPS
EPIGENETICS:
FROM MECHANISMS TO MEDICINES
A DMMC International Workshop
Mon 25 - Tue 26 June 2007
(Welcome Reception on Sun 24 June)
Venue: O’Reilly Hall, University College
Dublin (location)
This
Workshop has External Continuing Medical Education (CME) Credits
from the Royal College of Physicians of Ireland (8 Credits for Day
1 and 9 Credits for Day 2) and External Continuing Professional
Development (CPD) Credits from the Royal College of Physicians,
London (12 Credits).
Application
for this Workshop is open to Ireland-based and International Scientists
& Clinicians.
Registration
rates: €150
for students, €250 for others.
Registration has closed.
View
the Workshop Report (544KB PDF)
The
Epigenetics: From Mechanisms To Medicines workshop, open
to an Ireland-based and international audience, concentrates on
the latest developments worldwide in:
-
study
of epigenetic mechanisms;
-
techniques
and technologies used;
-
application
of knowledge of epigenetic mechanisms in the clinic.
In line
with the DMMC Education & Training remit to provide the knowledge
tools for translational medicine, this workshop is designed to encapsulate
current basic and clinical research and provide a glimpse of future
potential for an audience of bioscientists and physicians with an
interest in epigenetics.
Using
the excellent conference facilities of the O’Reilly Hall on
the University College Dublin campus, the Epigenetics: From
Mechanisms To Medicines workshop brings together internationally
renowned speakers, technology developers, and participants based
worldwide to interact in the lecture hall, in techniques sessions,
in poster sessions, and during informal gatherings. Outside of the
intensive two-day workshop schedule, participants may wish to sample
the historical sights and cosmopolitan atmosphere of Dublin or venture
further afield around Ireland.
| WELCOME
(Sunday 24 June) |
| 1700 |
Early
Registration |
| 1800-2000
Wine Reception with Music |
| |
| DAY
1: EPI-MECHANISMS
(Monday 25 June) |
| 0800 |
Registration
& Light Breakfast |
| 0825 |
Opening
of Workshop
Dr Mark Watson (DMMC) |
| 0830 |
Welcome
& Overview of Day 1
Dr Amanda McCann (University College Dublin) &
Dr Steven Gray (Trinity College Dublin) |
| |
|
| Session
1: CHROMATIN Chair:
Dr Steven Gray |
| 0840 |
Mechanisms
and Functions of Epigenetic Reprogramming in Mammalian Development
Prof Wolf Reik (The Babraham Institute, Cambridge, UK) abstract |
| 0930 |
Epigenetic
Aspects of Centromere Inheritance and Function
Prof Kevin Sullivan (National University of Ireland, Galway)
abstract
|
| |
|
| 1020 |
Coffee/Tea
+ Poster Viewing + Meet Our Sponsors |
| |
|
Session
2: RNA AS A REGULATOR
Chair:
Dr Amanda McCann |
| 1050 |
miRNAs
& Cancer Prof Orla Sheils (Trinity College Dublin)
abstract |
| 1140 |
Maternally
expressed microRNAs as trans-regulator at the callipyge locus?
Dr Carole Charlier (University of Liège, Belgium) abstract |
| |
|
| 1230 |
Poster
Talk 1 |
| |
|
Session
3: HISTONE MODIFICATIONS
Chair:
Prof Wolf Reik |
| 1240 |
The
Histone Code
Prof Bryan Turner (University of Birmingham, UK) abstract |
| |
|
| 1330 |
Lunch
+ Poster Viewing + Meet Our Sponsors |
| |
|
| 1430 |
Chemical
Biology Studies of Chromatin-Modifying Enzymes
Prof Stuart L. Schreiber (Broad Institute of Harvard
and MIT, USA) abstract |
| |
|
| 1520 |
Poster
Talk 2 |
| |
|
| 1530 |
TECHNIQUES
WORKSHOP 1
Discovery of DNA Hypermethylation Using a DHPLC Screening Strategy
Dr
Antoinette Perry (Trinity College Dublin) abstract |
| |
|
| 1610 |
Coffee/Tea
+ Poster Viewing + Meet Our Sponsors |
| |
|
| 1640 |
Poster
Talk 3 |
| |
|
| 1650 |
TECHNIQUES
WORKSHOP 2
A
Novel Method for Analysis of 5-Methylcytosine in DNA by Capillary
Electrophoresis Mobility Shift
Dr Mark Lynch (Application Specialist, Applied Biosystems) abstract |
| |
|
1730-1830
DAY 1 KEYNOTE LECTURE
(Sponsored by AIB) |
| |
Male-Line
Transgenerational Responses -
A New Aspect of Human Inheritance?
Prof Marcus Pembrey (UCL Institute of Child Health,
UK) abstract |
| |
|
| 1900 |
Workshop
Buffet Dinner with Jazz Band |
| DAY
2: EPI-THERAPEUTICS (Tuesday
26 June) |
| 0730 |
Light
Breakfast |
| 0800 |
Overview
of Day 2
Dr Amanda McCann (University College Dublin) & Dr Steven
Gray (Trinity College Dublin) |
| |
|
| Session
4: INTRODUCTION TO EPIGENETIC DRUGS Chair:
Dr Kay Nolan |
| 0810 |
An
Introduction to DNA Methyltransferase Inhibitors
Dr Helen Gallagher (University College Dublin) abstract |
| 0840 |
Histone
Deacetylase Inhibitors
Dr Steven Gray (Trinity College Dublin) abstract |
| |
|
| Session
5: STEM CELLS Chair: Prof Peter Jones |
| 0910 |
The
epigenetic landscape of stem cells
Dr Kay Nolan (University College Dublin) abstract |
| 0940 |
Stem
cell chromatin patterns - a blueprint for DNA hypermethlation?
Dr Joyce Ellen Ohm (Johns Hopkins University, USA) abstract |
| |
|
| 1030 |
Coffee/Tea
+ Poster Viewing + Meet Our Sponsors |
| |
|
| 1100 |
Poster
Talk 4 |
| |
|
Session
6: ENVIRONMENT INTERACTIONS
Chair:
Prof
Bryan Turner |
| 1110 |
Epigenetic
Transgenerational Actions of Endocrine Disruptors on
Reproduction, Disease and Evolution
Prof Michael Skinner (Washington State University, USA) abstract |
| 1200 |
Endocrine
Active Compounds and the Fetal Epigenome
Dr Dana Dolinoy (Duke University Medical Center, USA) abstract |
| |
|
| 1250 |
Lunch
+ Poster Viewing + Meet Our Sponsors |
| |
|
| 1350 |
Poster
Talk 5 |
| |
|
Session
7: EPIGENETICS & DISEASE
Chair: Dr Joyce Ellen Ohm |
| 1400 |
Imprinting
and ART (Assisted Reproductive Technology)
Prof Eamonn Maher (University of Birmingham, UK) abstract |
| 1450 |
DNA
Methylation and Haematological Malignancies
Prof Allen Yang (USC / Norris Comprehensive Cancer Center,
USA) abstract |
| |
|
| 1540 |
Coffee/Tea
+ Poster Viewing + Meet Our Sponsors |
| |
|
| 1610 |
Therapeutic
Potential of Targeting the Epigenome in Neurodegenerative Conditions
Dr Hoon Ryu (Boston University School of Medicine) abstract |
| 1700 |
Leaving
an Imprint on Cancer
Dr Amanda McCann (University College Dublin) abstract |
| |
|
| 1740 |
Announcement
of Poster Competition Winners |
| |
|
| 1745 |
DAY
2 KEYNOTE LECTURE
(Sponsored by the Irish Cancer Society) |
| |
Cancer
Epigenomics
Prof Peter Jones (USC / Norris Comprehensive Cancer Center,
USA) abstract |
| |
|
| 1845 |
Close
of Workshop |
| |
|
Workshop
Organisers
Dr
Amanda McCann (UCD Conway Institute of Biomolecular & Biomedical
Research)
Dr
Steven Gray (Institute of Molecular Medicine, St James’s
Hospital & TCD)
Dr Mark Watson (DMMC Education Coordinator)
Workshop
Faculty
Dr Carole Charlier (University of Liège, Belgium)
Dr
Dana Dolinoy (Duke University Medical Center, USA)
Dr
Helen Gallagher (UCD Conway Institute of Biomolecular &
Biomedical Research)
Prof
Peter Jones (USC / Norris Comprehensive Cancer Center, USA)
Dr Mark Lynch (Applied Biosystems)
Prof
Eamonn Maher (University of Birmingham, UK)
Dr
Kay Nolan (School of Biological and Environmental Science, UCD)
Dr Joyce Ellen Ohm (Johns Hopkins University, USA)
Prof
Marcus Pembrey (UCL Institute of Child Health, UK)
Dr
Antoinette Perry (Institute of Molecular Medicine, TCD)
Prof
Wolf Reik (The Babraham Institute, Cambridge, UK)
Dr Hoon Ryu (Boston University School of Medicine)
Prof
Stuart L. Schreiber (Broad Institute of Harvard and MIT, USA)
Prof
Orla Sheils (Trinity College Dublin)
Prof
Michael Skinner (Washington State University, USA)
Prof
Kevin Sullivan (National University of Ireland, Galway)
Prof Bryan
Turner (University of Birmingham, UK)
Prof
Allen Yang (USC / Norris Comprehensive Cancer Center, USA)
Workshop
Sponsors
Platinum
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