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DMMC COURSES & WORKSHOPS
DRUG DESIGN: PRINCIPLES & TECHNIQUES
19-20 & 23-24 April 2007 (0930
- 1300)
Venue: Albert Lecture Theatre, the Royal College of Surgeons in
Ireland (location)
Applications
are closed
Online application period: 12 Mar - 4 Apr 2007
This
course is designed to give clinicians and researchers from the life,
chemical and physical sciences a broad overview of the concepts,
strategies and research techniques used in drug discovery. Basic
understanding of molecular structures is assumed, but you should
not need prior knowledge of the models and techniques covered in
the course.
The objective for postgraduate teaching is to give students an overview
and illustrations of how proteins and other biologically active
molecules, targeted by or identified in laboratory research (in
silico or in vitro), can be studied to develop chemical agents mimicking
or interacting with them. This process can ultimately lead to the
development of new therapeutic candidates.
Follow
the links below to read an abstract of each lecture, together with
supplementary reading in some cases.
| Thu
12 Apr; 1100-1200 |
| 1100 |
The
Chemistry within the Pharmaceutical Industry
Prof
Bertrand Castro (Scientific Director Industrial Affairs, Sanofi-Aventis)
abstract |
| |
| Thu
19 Apr; 0930-1300 |
| 0930 |
From
genes to drugs Dr Marc Devocelle, RCSI abstract |
| 1015 |
Molecular
basis of drug action: drug receptor
interactions Dr Isabel Rozas, TCD abstract |
| 1100 |
Coffee/Tea |
| 1130 |
Molecular
basis of drug action: catalytic
receptors, enzymes and their inhibition
Dr John Gilmer, TCD abstract |
| 1215 |
Natural products as leads in drug
design
Dr James Barlow, RCSI abstract |
| |
|
| Fri
20 Apr; 0930-1300 |
| 0930 |
From sequences to consequences
Dr Marc Devocelle, RCSI abstract |
| 1015 |
The
concept of pharmacophore: biological
perspective Dr Niamh Moran, RCSI abstract |
| 1100 |
Coffee/Tea |
| 1130 |
The concept of pharmacophore: informatics
perspective Prof Denis Shields, UCD abstract |
| 1215 |
Synthetic
molecules as drugs: macromolecules
Dr Raphael Darcy, UCD abstract |
| |
|
| Mon
23 Apr; 0930-1300 |
| 0930 |
Rational drug design: structure/activity
relationships Dr Isabel Rozas, TCD abstract |
| 1015 |
Rational computer-aided
drug design
Dr Darren Fayne, TCD abstract |
| 1100 |
Coffee/Tea |
| 1130 |
Techniques in rational
drug design: X-ray
crystallography Dr Amir Khan, TCD abstract |
| 1215 |
The impact of Regulatory
Affairs in Drug Discovery
Dr Chantal Le Floch, Servier biography |
| |
|
| Tue
24 Apr; 0930-1300 |
| 0930 |
The
role of drug delivery in drug design and
drug development
Dr Sally-Ann Cryan, RCSI abstract |
| 1015 |
Drug delivery: from
molecular packaging to
targeting Dr Raphael Darcy, UCD abstract |
| 1100 |
Coffee/Tea |
| 1130 |
IP
issues in drug design
Mr Barry Purdy, Purdy & Company abstract
|
| 1215 |
Case
studies in drug discovery and design
Dr Mary Meegan, TCD abstract |
Course Coordinator
Dr
Marc Devocelle (Department of Pharmaceutical Chemistry, RCSI)
Course Instructors
Dr
James Barlow (School of Pharmacy, RCSI)
Dr
Sally-Ann Cryan (School of Pharmacy, RCSI)
Dr
Raphael Darcy (UCD School of Chemistry & Chemical Biology
and Conway Institute)
Dr
Darren Fayne (Molecular Design Group, School of Biochemistry
and Immunology, TCD)
Dr
John Gilmer (School of Pharmacy & Pharmaceutical Sciences,
TCD)
Dr Amir
Khan (School of Biochemistry and Immunology, TCD)
Dr
Chantal Le Floch (Pre-submission
Division Director (Worldwide Regulatory Affairs), Servier
Research Group)
Dr
Mary Meegan (School of Pharmacy & Pharmaceutical Sciences,
TCD)
Dr
Niamh Moran (Department of Clinical Pharmacology, RCSI)
Mr Barry Purdy (European Patent Attorney, Purdy & Company)
Dr
Isabel Rozas (School of Chemistry, TCD)
Prof
Denis Shields (UCD Conway Institute of Biomolecular & Biomedical
Research)
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