DMMC Course: TECHNIQUES & STRATEGIES IN MOLECULAR MEDICINE

1530-1615 Thursday 7 December 2006. UCD Conway Instutute Lecture Theatre, UCD

High Content Screening and Analysis Platform technologies
Dr Anthony Davies (Institute of Molecular Medicine, TCD)

High Content Screening and Analysis (HCS(A)) is becoming synonymous with the reporting of biochemical events occurring within individual cells. This new technology now permits visualisation and quantitation of a wide range of target-specific responses on a per cell basis. HCA technologies are now capable of providing a highly detailed picture of a cells physiological state. This technology allows for the first time a quantitative assessment of gross morphology, sub-cellular target localisation, cell viability, apoptosis and cytoskeletal rearrangement of single cells in populations.

Here at IMM Trinity we have already successfully utilised HCA technologies in cell-based cancer, inflammation and infection cardiovascular and immunity studies.

In the Techniques and Strategies in Molecular Medicine course, we will cover the fundamental aspects of HCA technology deployment and utilisation. This will form a solid foundation, on which to build further knowledge and experience in this new and exciting scientific discipline.