DMMC Course: MOLECULAR CELL BIOLOGY IN ACTION

1000-1120 Monday 10 January 2005. Conway Institute Lecture Theatre, UCD

Basic molecular cell biology mechanisms Dr John Baugh, UCD

This session will briefly introduce many of the basic molecular events that govern cellular function, and help set the foundation for the following advanced translational seminars. Starting in the nucleus of a eukaryotic cell we will track the processes of DNA replication and gene expression. Newly formed RNA transcripts will then be followed to the cytoplasm where they undergo translation and processing to mature protein gene products. Ending with a brief overview of protein trafficking, secretion and proteosomal degradation we will complete the basic molecular cascade that is essential to all cellular functions.