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DMMC COURSES & WORKSHOPS

CANCER BIOLOGY TO CANCER MEDICINE
24 - 26 May 2006; 1345-1730 on Wed, 0900-1800 on Thu, 0900-1400 on Fri.
Venue:
Durkan Lecture Theatre, Institute of Molecular Medicine, TCD, St James's Hospital (location)
Online application is closed
Online application period: 19 Apr - 19 May 2006
(at 1200)

Application for this course is open to researchers throughout Ireland.

This DMMC course is designed to provide an overview of the main cellular and molecular processes involved in cancer development and progression, defining these processes in detail in a selected number of human malignancies. It will show how an increasing knowledge of cancer development and progression at the molecular level is providing a conduit for the application of molecular medicine in cancer diagnostics and cancer therapeutics.

Comprising a series of lectures, round-table tutorials, specific disease focus lectures and case studies, the course aims to make participants aware not only of the underlying principles of cancer, but also of the practicalities in translating this knowledge for clinical benefit. Faculty for the course is drawn from both within and outside the DMMC, bringing together a cadre of experts to provide state-of-the-art knowledge and practical experiences in this important discipline.

Follow the links below to read abstracts of most lectures, together with supplementary reading in some cases.

Wed 24 May; 1345-1730
1345 Course introduction Prof Mark Lawler (St James's
Hospital & TCD)
1350 The hallmarks of cancer
Prof Mark Lawler abstract
1430 Genes and cancer Prof Mark Lawler abstract
1510 Cell signalling and cancer Dr Aideen Long (TCD)
abstract
Reading List (13.7 KB PDF)
1550 Coffee/Tea
1620 Apoptotic pathways in cancer development
Dr William Watson (UCD) abstract

1650 Disease Focus I: Lymphoma
Dr Elizabeth Vandenberghe (St James's Hospital &
TCD), Prof Mark Lawler abstract

Thu 25 May; 0900-1800
0900 Angiogenesis and cancer
Dr Judy Harmey (RCSI) abstract
0930 Metastasis and cancer Dr Susan McDonnell (UCD)
abstract
1000 Disease Focus II: Oesophageal and GI cancers,
genetics and environmental influences
Prof John Reynolds (St James's Hospital & TCD)
Second speaker to be confirmed
1050 Coffee/Tea
1120 Round Table I: Genomic instability and cancer
Moderators: Dr Emer Bourke & Dr Ciaran Morrison
(NUI, Galway)
Pre-Reading 1 (9.28 MB PDF)
Pre-Reading 2 (1.88 MB PDF)
Pre-Reading 3 (692 KB PDF)
1300 Lunch
1400 Disease Focus III: Understanding prostate
cancer, cellular and molecular clues

Dr William Watson (UCD), Dr David Waugh (Queens
University Belfast) abstract
1450 BRCA1 signalling and cancer Dr Paul Mullan
(Queens University Belfast) abstract
1510 Coffee/Tea
1540 Round Table II: Biomarkers and molecular
pathology
Moderators: Prof Elaine Kay (RCSI),
Dr Orla Sheils (TCD) abstract
Pre-reading (806 KB PDF)
1700 State of the Art Lecture I: Molecular basis of
cancer metastasis-potential therapeutic targets
Prof Ian Hart (Department of Tumour Biology,
Bart's & The London
)
1800 Feedback and end of day 2

Fri 26 May; 0900-1400
0900 Cancer drug development
a) Apoptosis as a therapeutic target for early
clinical trials Dr Dean Fennell (Queens
University Belfast) abstract
b) Taking the target forward - working towards
novel anti-apoptotic candidates
Dr David Lloyd (TCD) abstract
0950 Signal transduction pathways as targets for
cancer therapeutics
Dr Aideen Long (TCD)
abstract
1020 Case Studies: Molecular medicine in action
Prof Mark Lawler (St James's Hospital & TCD),
Dr Stephen Langabeer (St James's Hospital)
abstract

1100 Coffee/Tea
1130 Round Table III: 'Omics in cancer medicine
Moderators: Prof John O'Leary (St James's Hospital
& TCD), Prof Stephen Pennington (UCD)
1300 State of the Art Lecture II: Clinical trial designs
for early drug development

Dr Jennifer Low (National Cancer Institute,
Washington, USA)
abstract
1345 Round Up and End of the Course

Course Coordinator
Prof Mark Lawler (Institute of Molecular Medicine, St James’s Hospital & TCD)

Course Instructors
Dr Emer Bourke (Department of Biochemistry and NCBES, National University of Ireland, Galway)
Dr Dean Fennell (Centre for Cancer Research & Cell Biology, Queens University Belfast)
Dr Judy Harmey (Department of Surgery, RCSI)
Prof Elaine Kay (Department of Pathology, RCSI)
Dr Stephen Langabeer (Cancer Molecular Diagnostics, St James's Hospital)
Dr Aideen Long (
Institute of Molecular Medicine, St James's Hospital & TCD)
Dr David Lloyd (Molecular Design Group, School of Biochemistry and Immunology, TCD)
Dr Susan McDonnell (School of Chemical & Bioprocess Engineering, UCD)
Dr Ciaran Morrison (Department of Biochemistry and NCBES, National University of Ireland, Galway)
Dr Paul Mullan (Centre for Cancer Research and Cell Biology, Queen's University Belfast)
Prof Stephen Pennington (UCD Conway Institute of Biomolecular & Biomedical Research)
Dr Orla Sheils (
Institute of Molecular Medicine, St James's Hospital & TCD)
Dr Elizabeth Vandenberghe (St James's Hospital & TCD)
Dr William Watson (UCD Conway Institute of Biomolecular & Biomedical Research)

Dr David Waugh (Centre for Cancer Research & Cell Biology, Queens University Belfast)

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