DMMC COURSES & WORKSHOPS

CANCER BIOLOGY TO CANCER MEDICINE I
26 - 27 May 2005; 0900-1600 on Thu, 1000-1300 on Fri
Venue: Montgomery Lecture Theatre, Trinity Centre for Health Sciences, St James's Hospital (location)
Application for this course is open to researchers throughout Ireland.
(please apply separately for each part of this course)

Course Coordinator: Prof Mark Lawler (Institute of Molecular Medicine, St James’s Hospital & TCD)

This DMMC course is designed to provide an overview of the main cellular and molecular processes involved in cancer development and progression, defining these processes in detail in a selected number of human malignancies. It will show how an increasing knowledge of cancer development and progression at the molecular level is providing a conduit for the application of molecular medicine in cancer diagnostics and cancer therapeutics. Comprising a series of lectures, round-table tutorials, specific disease focus lectures and case studies, the course aims to make participants aware not only of the underlying principles of cancer, but also of the practicalities in translating this knowledge for clinical benefit. Faculty for the course is drawn from both within and outside the DMMC, bringing together a cadre of experts to provide state-of-the-art knowledge and practical experiences in this important discipline.

The course is in two parts: Cancer Biology to Cancer Medicine I (contents below) runs 26-27 May, while Cancer Biology to Cancer Medicine II takes place 7-8 July. Taken together, both parts of the course are designed to provide a wide-ranging look at our current understanding of cancer and the practicalities of translational research in this area. We strongly recommend that those interested attend both parts of the course - please apply online separately for each part. It is advisable to apply early to ensure a place.

Day 1, Thu 26 May; 0900-1600

0900 Course Introduction
Prof Mark Lawler (IMM, TCD)
0915 The Hallmarks of Cancer
Prof Mark Lawler (IMM, TCD)
1000 Cell Signalling and Cancer
Dr Aideen Long (Dept of Biochemistry, RCSI)

1045 Coffee/Tea

1115 Genetics of Inherited Cancers
Dr Ross McManus (IMM, TCD)
1200 Metastasis and Cancer
Dr Susan McDonnell (Dept of Chemical and Biochemical Engineering, UCD)

1245 Lunch

1345 Round Table I: Epigenetics and Cancer
Moderators:
Dr Amanda McCann (Conway Institute, UCD)
Dr Steven Gray (IMM, TCD)
The following papers will be discussed (follow the links to the PubMed entries):
Feinberg AP, Tycko B.
The history of cancer epigenetics.
Nat Rev Cancer. 2004 Feb;4(2):143-153.
Murrell A, Rakyan VK, Beck S.
From genome to epigenome.
Hum Mol Genet. 2005 Apr 15;14 Spec No 1:R3-R10.
Further reading

1515 Disease Focus I: Molecular Basis of Haematological Malignancies
Prof Mark Lawler (IMM, TCD)

Day 2, Fri 27 May; 1000-1300

1000 Angiogenesis and Cancer
Dr Judy Harmey (Dept of Surgery, RCSI)
1045 Disease Focus II: Understanding Prostate Cancer, Cellular and Molecular Clues
Dr Bill Watson (Conway Institute, UCD)
1130 Gene Transcription in Cancer
Prof Mark Lawler (IMM, TCD)
1200 Gene Expression Profiling - What to do With the Data? Dr Aedín Culhane (Conway Institute, UCD)
1230 Case Studies I: Molecular Medicine in Action
Lymphoma Dr Elizabeth Vandenberghe (St James’s Hospital & TCD)

1300 Round Up and End of Part I of the Course